What is hepatic epithelioid hemangioendothelioma?

Hepatic epithelioid hemangioendothelioma (EHE) is a very rare malignant vascular tumor composed of epithelioid and histiocytoid endothelial cells in a myxohyaline or fibrous stroma. It may also occur in the lungs, soft tissue and bone.

What causes epithelioid hemangioma?

Epithelioid hemangioma is sometimes caused by injury and often comes back after treatment. Epithelioid hemangioma is most common in young and middle-aged adults. It is a type of vascular tumor. Also called angiolymphoid hyperplasia with eosinophilia and histiocytoid hemangioma.

Is epithelioid hemangioendothelioma malignant?

Background. Epithelioid hemangioendothelioma (EHE) is a rare malignant vascular neoplasm with increasing incidence. However, its clinical characteristics remain unclear due to its low incidence.

Is epithelioid hemangioendothelioma a sarcoma?

Epithelioid Hemangioendothelioma (EHE) is a rare cancer that belongs to the group of cancers called sarcomas. EHE is a vascular sarcoma. This means it originates in the cells that line the inside of blood vessels. ‘Epithelioid’ refers to the elongated shape of the cells when seen under the microscope.

What is hemangioendothelioma?

The term hemangioendothelioma describes several types of vascular neosplasms and includes both non-cancerous (benign) and cancerous (malignant) growths. The term has also been applied to those that show “borderline” behavior, intermediate between entirely benign hemangiomas and highly malignant angiosarcomas.

What is infantile hemangioendothelioma?

Infantile hemangioendothelioma is a rare benign vascular tumor of the liver. We report a case of hepatic hemangioendothelioma in an 8- month-old female infant who presented with hepatomegaly and respiratory distress, which was successfully treated with oral prednisolone for six months.

What does hemangioendothelioma mean?

What is a hemangioendothelioma?

Hemangioendothelioma is the term used to name those vascular neoplasms that show a borderline biological behavior, intermediate between entirely benign hemangiomas and highly malignant angiosarcomas.

What causes Hemangioendothelioma?

Hemangioendotheliomas are caused by abnormal growth of blood vessel cells , although the exact underlying cause for the abnormal growth is unknown. They can also develop in an organ , such as the liver or lung. They usually grow slowly and can sometimes spread to other tissues in the body (metastasize).

Is epithelioid hemangioendothelioma curable?

Although localized epithelioid hemangioendothelioma can be surgically resected, there is no effective therapy for systemic disease, and mortality from the cancer ranges between 13% and 18% when confined to soft tissue, but life expectancy in metastatic cases is unpredictable and ranges from a couple of months to 15 to …

What does Hemangioendothelioma look like?

These tumors are so named because their histologic appearance resembles a proliferation of epithelioid cells, with polygonal shape and eosinophilic cytoplasm. Composite hemangioendothelioma is a low-grade angiosarcoma typically occurring in adults, although it has been described in infancy.

What is a hamartoma liver?

Mesenchymal hamartoma of the liver is a benign tumor of infancy characterized by an admixture of epithelial structures in a loose connective tissue stroma with fluid accumulation suggestive of lymphangiomatous channels.